| |
Clinical Services – Molecular Genetic Testing
Molecular genetics aids in the understanding of genetic mutations that can cause certain types of diseases. Molecular genetic testing identifies the following:
Changes in genes (missing or additional sections of a gene).
Changes in chemical bases within the DNA strand (i.e. missing, additional or altered bases).
Genes with too many copies, hyperactive genes, and silenced genes.
Example of DNA Sequencing Results:
Available Molecular Biology Testing:
IGHV Mutation (CLL)
JAK2 V617F mutation (MPN)
JAK2 Exon 12 mutation (MPN)
MPL 515/505 mutation (MPN)
T-Cell Clonality (TCRβ) (Lymphoma)
T-Cell Clonality (TCRγ) (Lymphoma)
B-Cell Clonality (IGH) (Lymphoma)
BCR/ABL Qualitative (CML)
BCR/ABL Quantitative (CML)
BCR/ABL 1 Kinase domain mutation (CML)
KRAS mutation (CRC, NSCLC)
BRAF mutation (CRC)
EGFR mutation (CRC, NSCLC)
NRAS mutation (CRC)
NPM1 mutation (AML)
FLT3 mutation (AML)
|
|
|
